Semen Allergy

Semen Allergy may technically be called Human Seminal Plasma Hypersensitivity.

As with any substance, it’s possible to be allergic to seminal fluid. It is estimated that five percent of women are allergic to semen.

The symptoms of semen allergy can either be a localized or systemic reactions.
The localized reactions, can be an intense burning after intercourse. Some women have vaginal burning, pain, swelling, redness, or even blisters forming within 30 minutes of exposure to semen.

Others may have systemic reactions that include generalized itching, hives, angioedema, wheezing, and in very rare cases anaphylaxis. Anaphylaxis is an acute, intense reaction of the body against the allergen which may even be fatal.


Exact cause of semen allergy is not known. There is a theory that connects it to food allergies because of similar protein composition. 

Semen contains very modest quantities of the following substances: aboutonia, ascorbic acid, blood-group antigens, calcium, chlorine, cholesterol, choline, citric acid, creatine, deoxyribonucleic acid, fructose, glutathione, hyaluronidase, inositol, lactic acid, magnesium, nitrogen, phosphorus, potassium, purine, pyrimidine, pyruvic acid, sodium, sorbitol, spermidine, spermine, urea, uric acid, vitamin B12, and zinc.


There are number of diagnostic procedures available to help determine this allergy. These include some hyposensitivity tests. Another sure way to determine if a semen allergy exists is to try using condoms. If there is no reaction after intercourse on using condoms, semen allergy does exists.


Hyposensitization treatment is available for this problem. This treatment is similar to the effects of allergy shots. Your body is desensitized to the allergic effect of semen by gradually increasing the amount of semen you’re exposed to.

Meanwhile, educate your mate regarding your problem and always use a condom during sexual intercourse.